GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs160648 | chr7:65543384 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.47 | 3.66E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs160652 | chr7:65538431 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs160655 | chr7:65533214 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.47 | 3.66E-7 | Diabetic kidney disease |
| THYM | cis | rs9815354 | 1 | rs1607908 | chr3:41905196 | ULK4 | chr3:41288091-42003660:- | 1.02 | 11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs881375 | 1 | rs1609810 | chr9:123642351 | LOC253039 | chr9:123605320-123616644:+ | -0.62 | -5.59 | 2.21E-7 | Rheumatoid arthritis |
| THYM | cis | rs7301826 | 1 | rs1609985 | chr12:131320170 | STX2 | chr12:131274149-131323811:- | 0.36 | 6.02 | 3.27E-8 | Plasma plasminogen activator levels |
| THYM | cis | rs9815354 | 1 | rs1612124 | chr3:41967893 | ULK4 | chr3:41288091-42003660:- | -0.96 | -10.38 | 2.59E-17 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs1613759 | chr3:41906183 | ULK4 | chr3:41288091-42003660:- | 1 | 11.02 | 1.12E-18 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs1615243 | chr3:41965234 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.59 | 6.88E-20 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs1615543 | chr3:41906404 | ULK4 | chr3:41288091-42003660:- | 1 | 11.02 | 1.12E-18 | Diastolic blood pressure |
| THYM | cis | rs2243480 | 1 | rs1618893 | chr7:66096119 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.84 | 5.03E-6 | Diabetic kidney disease |
| THYM | cis | rs9815354 | 1 | rs1628874 | chr3:41955714 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.47 | 1.23E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs1629460 | chr3:41927449 | ULK4 | chr3:41288091-42003660:- | -1 | -11.02 | 1.12E-18 | Diastolic blood pressure |
| THYM | cis | rs1633360 | 1 | rs1633360 | chr12:58108052 | TSFM | chr12:58176536-58191367:+ | 0.22 | 4.16 | 7.08E-5 | Rheumatoid arthritis |
| THYM | cis | rs1499614 | 1 | rs1638731 | chr7:66144679 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Gout |